Slay the Spire 2 — Card Database, Deck Builder & Guide (March 2026)

At the start of each combat, gain 8 Vigor .

Upon pickup, gain 4 potion slots filled with random potions.

Enemies drop 10 additional Gold .

Start each combat with 10 Block .

Upon pickup, obtain a random Rare Card to add to your Deck .

Upon pickup, Transform a starter card with an ancient version.

If you do not play any Attacks during your turn, gain an additional next turn.

Upon pickup, Transform 3 cards, then Upgrade them.

At the start of each combat, apply 1 Vulnerable to ALL enemies.

At the start of each combat, draw 2 additional cards.

You cannot lose more than 20 HP in a single turn.

Upon pickup, choose 3 cards in your Deck . Enchant them with Swift 3 .

The first Hand you draw each combat is Upgraded .

While you have no potions, you have 2 additional Dexterity .

At the start of each combat, add 2 random Ethereal cards into your Hand .

Upon pickup, raise your Max HP by 20 . At the start of each combat, draw 2 fewer cards.

Upon pickup, remove 4 cards from your Deck . Whenever you shuffle your Draw Pile , add a Soot into your Draw Pile .

Whenever you add a card to your Deck , add one additional copy.

At the end of combat, heal 12 HP.

Elites drop an additional Relic when defeated.